Thiolated Chitosans: Novel Polymers for Mucoadhesive Drug Delivery – A Review
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چکیده
منابع مشابه
Thiolated Chitosans: Novel Polymers for Mucoadhesive Drug Delivery – A Review
Chitosan is a natural polycationic copolymer consisting of glucosamine and N-acetylglucosamine units. The polymer has valuable properties as a biomaterial because it is considered to be biocompatible, biodegradable and non-toxic. The purpose of this review article is to provide detailed information about thiolated chitosans which are gaining popularity because of their high mucoadhsiveness and ...
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The successful development of multifunctional drug delivery systems is mainly based on the development and evaluation of new mucoadhesive polymers. Chitosan is a natural polycationic copolymer consisting of glucosamine and Nacetylglucosamine units. The polymer has valuable properties as a biomaterial because it is considered to be biocompatible, biodegradable and non-toxic. The derivatization o...
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The purpose of this study was to synthesize and characterize a novel thiolated glycogen, so-named S-preactivated thiolated glycogen, as a mucosal drug delivery systems and the assessment of its mucoadhesive properties. In this regard, glycogen-cysteine and glycogen-cysteine-2-mercaptonicotinic acid conjugates were synthesized. Glycogen was activated by an oxidative ring opening with sodium peri...
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ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2008
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v7i3.14694